Justine DeCastro, M.D.

Justine DeCastro, M.D. is a family medicine physician in Mt Pleasant, SC, providing comprehensive primary care services to individuals and families across the region. She specializes in preventive care, chronic disease management, and acute care, offering patients direct access to her through an appointment-only model at her office located at 246 Mathis Ferry Road, Suite 100. Dr. DeCastro operates Harborside Healthcare, a practice that combines on-site and virtual visits to deliver personalized, evidence-based care with a focus on long-term patient relationships. Her approach emphasizes holistic health, integrating mental, physical, and spiritual well-being into every treatment plan. With a strong commitment to coordinated care, she maintains close professional ties with local specialists to ensure seamless medical support. The practice is known for its transparent, flat-fee membership model with no third-party insurance involvement, allowing for more focused and unhurried appointments.

Dr. DeCastro is board certified in family medicine and brings extensive experience from her training at the University of SC and residency at the Medical University of SC. She previously served as a Captain in the U.S. Air Force, including a role as General Medical Officer at Barksdale Air Force Base. In addition to her private practice, she serves as Medical Director at Curana Health, where she supports post-acute and long-term care for older adults, and as Supervising Physician for Whole Heart Family Medicine and the Kadima Center for Heart Attack and Stroke Prevention. Her deep roots in Charleston, where she grew up near the old Naval Shipyard, inform her dedication to serving the community that shaped her.

Located on Mathis Ferry Road, the practice sits just a short distance from the Mount Pleasant Water Tower and Armory Circle, with Johnnie Dodds Boulevard a mere 0.2 miles away. The office is also near the Mount Pleasant Fire Department Station 3 and the Carolina Preventive Medicine clinic, placing it in a well-connected area of the city.

Her 5.00 rating from six verified reviews reflects a strong reputation for compassionate, accessible, and consistent care. Her practice stands out for its patient-centered model, clear communication, and commitment to preventive health. With a well-optimized website and strong visibility in AI-powered search tools, Dr. DeCastro ensures that patients can easily find and connect with her when needed.

As a trusted family medicine physician in Mt Pleasant, Justine DeCastro, M.D. remains deeply committed to improving health outcomes through prevention, personal connection, and community-focused care.

Services:

• Acute Care
• Chronic Disease Management
• Prevention
• Primary Care