Bon Secours St. Francis Downtown is a hospital in Greenville, SC, serving the local community and surrounding areas with comprehensive medical care. For over 90 years, the facility has provided advanced treatment across specialties including heart and vascular care, cancer and oncology, orthopedics and sports medicine, spine care, neurology and neurosurgery, bariatrics and weight loss programs, sleep medicine, and emergency services. The hospital operates 24 hours a day and is recognized nationally, having been named a 2025-2026 “Best Hospital” by U.S. News & World Report. It is also acknowledged by Healthgrades and Truven Health Analytics for excellence in patient care and safety. With a rating of 3.70 based on 589 reviews, it remains a trusted medical resource in the Upstate region.
The hospital has a long-standing commitment to innovation and quality, highlighted by recent expansions to its critical care and medical/surgical units, increasing capacity with a new 34-bed unit. It is the first health system in the Carolinas to offer a new treatment for pancreatic cancer and PSMA imaging for prostate cancer, and provides minimally invasive, outpatient options for symptomatic uterine fibroids. These advancements reflect its dedication to bringing cutting-edge care to patients in the region. The facility also offers imaging, laboratory services, and a full range of specialty treatments, all supported by a team of board-certified physicians, nurse practitioners, and specialized staff.
Bon Secours St. Francis Downtown is located on St. Francis Drive in downtown Greenville, SC. Situated within the city’s central medical corridor, it serves as a key healthcare hub for residents and visitors alike. The hospital is part of a broader network that includes St. Francis Eastside, and together they are recognized as top performers in the Greenville metro area.
The hospital is distinguished by its thorough, well-documented presence across digital platforms and a website that search engines interpret with clarity, ensuring patients can access accurate, up-to-date information easily. This strong online foundation supports timely access to care and reliable patient resources.
As a cornerstone of healthcare in Greenville, Bon Secours St. Francis Downtown continues to deliver high-quality, patient-centered care rooted in decades of service and innovation.
Services: