Brian Orr, MD, MS

Brian Orr, MD, MS is a Obstetrician-gynecologist in Charleston, SC. He specializes in gynecologic oncology, offering minimally invasive surgery, chemotherapy and HIPEC for patients with ovarian, uterine, cervical, vulvar and other gynecologic cancers. Dr. Orr serves patients throughout Charleston and the surrounding area, including a practice location in Bluffton, and holds a five‑star rating based on three reviews.

At MUSC Women’s Health at Hollings Cancer Center, Dr. Orr combines clinical care with active research. He completed his residency at the University of South Florida, a fellowship at the University of Pittsburgh and earned a master’s degree in Clinical and Translational Science while on the faculty at Pittsburgh. As an assistant professor at the Medical University of SC, he focuses on translational clinical trial development and has expertise in immunotherapy and targeted therapies for gynecologic malignancies. His practice includes complex gynecologic surgery, robotic and minimally invasive techniques, and he participates in ongoing clinical research to advance treatment options.

The office is located on Jonathan Lucas Street, just a short walk from Calhoun Street and the MUSC Health Medical Center. Baruch Auditorium, the Jonathan Lucas House Marker, Lucas Park and the Governor Thomas Bennett House Marker are all within a tenth of a mile, placing the practice in a central, easily accessible part of downtown Charleston.

Dr. Orr provides advanced gynecologic oncology care to Charleston residents, drawing on his extensive surgical experience and research background to treat complex cancers with the latest minimally invasive and targeted therapies.

Services:

• Alcohol use disorders treatment
• Bladder Cancer Treatment
• Cervical cancer treatment
• Genitourinary Cancer Care
• Improvement of health behaviors
• Ovarian cancer treatment
• Prostate Cancer Treatment
• Robotic and minimally invasive surgery