Miss Shirley's Cafe, Inner Harbor is a restaurant in Baltimore, MD, specializing in breakfast, brunch, and lunch with a focus on Southern-inspired cuisine and locally sourced ingredients from the Chesapeake Bay region. Located at 750 E Pratt St, the cafe serves guests in the Inner Harbor area and surrounding neighborhoods, offering a curated menu that highlights seasonal and regional flavors. Known for its award-winning culinary experience, the restaurant holds a 4.50 rating from guests, reflecting consistent praise for its food quality, service, and ambiance. Diners enjoy specialties such as Chicken ‘N Waffles, Shrimp & Grits, Crab Hash, Fried Green Tomato Eggs Benedict, and Coconut Cream Stuffed French Toast, alongside signature drinks like the Chesapeake Crush and Pineapple Coconut Coolada.
Founded in 2005 by Baltimore native Eddie in memory of his close friend and former colleague Miss Shirley, the cafe was established as a tribute to her vibrant spirit and love of cooking. Her image, along with Eddie’s, is displayed in each location as a lasting homage to their professional bond in the 1980s. The culinary direction is led by Corporate Executive Chef Zuri Coles, who develops seasonal menus that blend southern tradition with fresh, local ingredients. The menu includes a variety of options such as fresh cracked omelets, house-made French toast, and allergen-friendly selections, with dedicated kids’ and family meal offerings. The cafe also operates a second location in Roland Park and offers services at BWI Airport, with online ordering and delivery available during operating hours.
Miss Shirley's Cafe has earned recognition across Maryland for excellence in breakfast and brunch, including being named Best Breakfast/Brunch and Best Gluten-Free Options by The Baltimore Sun, and Best Local Restaurant for Kids by Baltimore's Child Magazine. It has also received accolades for its inclusive dining options and seasonal offerings, with features in publications such as Fast Food Club, WJZ 13 News, and Tasting Table. The restaurant continues to serve as a community staple, supporting local events and charitable initiatives while maintaining a welcoming, well-maintained environment for all guests.
In Baltimore’s vibrant food scene, Miss Shirley's Cafe stands out for its deep-rooted connection to local culture, seasonal creativity, and enduring commitment to quality, making it a cherished destination for brunch and beyond.