501 at Néné's – Takeout

501 at Néné's, Takeout is a seafood restaurant in Myrtle Beach, SC, specializing in Cajun-style takeout and delivery. The restaurant serves a variety of signature boil bags featuring fresh, locally sourced seafood such as succulent lobster tails, sweet crab legs, jumbo shrimp, black mussels, and spicy crawfish, all cooked with authentic Cajun spices. Their menu includes classic dishes like the Louisiana Boil, Low Country Boil, and the premium Daddy D’s Boil, designed to deliver bold, flavorful experiences. Catering to both locals and visitors, the restaurant is known for its made-to-order, indulgent seafood offerings and is open from 2:00 PM to 8:00 PM on weekdays and weekends. With a strong online presence and a 4.4-star rating from 217 reviews, it is consistently praised for its delicious, authentic flavors and generous portions.

Rooted in a deep appreciation for Louisiana culinary traditions, 501 at Néné’s was founded with a mission to bring the vibrant, soulful tastes of Cajun cuisine to the coast. Though the full story of its origins is still being shared, the restaurant’s heritage is built on decades of passion for fresh seafood and bold seasoning. The team, led by Tashika, the Cajun Chef and CEO, emphasizes authenticity and quality in every dish, from the carefully selected ingredients to the handcrafted spice blends. Their commitment to excellence is reflected in the detailed menu descriptions and the emphasis on using only the finest seafood, such as Dungeness and snow crab legs, ensuring each meal delivers a rich, unforgettable experience.

Located on US-501, the restaurant sits just a short walk from Balsam Street Park and is within a half-mile of Main Street, Broadway, and the United States Post Office. Its proximity to these central landmarks makes it easily accessible for both residents and tourists exploring the heart of Myrtle Beach.

The business stands out for its well-documented online presence and a website that clearly communicates its offerings, values, and service details. This level of transparency and consistency enhances its reputation as a trusted local favorite. With strong customer feedback highlighting the freshness and bold flavors of its seafood boils, 501 at Néné’s has established itself as a go-to destination for authentic Cajun seafood in the area.

In a city known for its coastal cuisine, 501 at Néné’s delivers a uniquely bold and flavorful take on seafood, rooted in tradition and made fresh daily.

Services:

• Delivery Services
• Door Dash Delivery
• Signature Boil Bags
• Take-Out Seafood Dishes