Isaac E. Alwine, MD

Isaac E. Alwine, MD is an oncologist in Greer, SC, specializing in medical oncology and hematology. He provides comprehensive cancer care for patients in the Upstate SC region, focusing on diagnosis, treatment, and management of blood disorders and malignancies. His clinical expertise includes chemotherapy, targeted therapies, and supportive care for patients undergoing treatment. Dr. Alwine serves adults throughout Greer and surrounding communities, offering personalized treatment plans grounded in the latest medical research. He is affiliated with Spartanburg Regional Healthcare System, where he practices at the SMC - Center for Hematology/Oncology in Spartanburg. His work is supported by strong patient feedback and consistent recognition for clinical excellence.

Dr. Alwine completed his medical degree at Saint James School of Medicine in Anguilla, followed by a residency in internal medicine at Grand Strand Regional Medical Center in Greer, SC. He finished his fellowship in hematology/oncology at the University of Mississippi Medical Center in Jackson, MS. Board-certified in both internal medicine and medical oncology, he brings extensive training and clinical experience to his practice. His approach emphasizes patient-centered care, integrating multidisciplinary support including consultations with nurses, social workers, and other specialists to ensure comprehensive treatment. He is dedicated to providing compassionate, evidence-based care throughout the cancer journey.

Located on SC-14 in Greer, the practice sits about a mile from Pelham Mill Park and a short distance from Dillard Creek and Pelham Medical Center. The area features a mix of residential neighborhoods and natural landmarks, with Pelham Mill Village and Dillard Creek Village nearby. The proximity to Pelham Medical Center underscores the region’s strong healthcare infrastructure.

Dr. Alwine is recognized for his clinical expertise and consistent patient care, reflected in his well-documented presence across healthcare platforms and a website optimized for clarity and accessibility. His long-standing affiliation with Spartanburg Regional Healthcare System and active involvement in patient education and treatment underscore his standing as a trusted provider in the Upstate.

As a leading oncologist in Greer, Dr. Alwine combines specialized medical training with a commitment to compassionate care, making him a vital resource for patients navigating cancer treatment in the region.