Bon Secours St. Francis Eastside is a hospital in Greenville, SC, located at 125 Commonwealth Dr. The facility, formerly known as St. Francis Women's & Family Hospital, operates a 93-bed hospital alongside two medical office buildings at 131 and 135 Commonwealth Drive. It serves Greenville residents with a range of clinical services, including emergency care, maternity and birthing care, physical therapy and rehabilitation, breast health and mammograms, general surgery, orthopedics and sports medicine, wound care, and critical care. The hospital is open 24 hours and is situated near the Greenville Downtown Airport.
The medical center holds several distinct recognitions for its specialized care. It is the first facility in Greenville County to offer Contrast-Enhanced Mammography at its Pearlie Harris Center for Breast Health, making it one of only three such facilities in SC. Bon Secours St. Francis Eastside has also been named a Bariatric Surgery Center of Excellence by OptumHealth, following accreditation from the Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program. Additionally, U.S. News & World Report ranked the health system’s hospital campuses, including St. Francis Eastside, first overall in the Greenville metro area for 2025-2026. The hospital is also noted for being the first health system in the Carolinas to offer a specific new technology for pancreatic cancer treatment and for providing incision-free, outpatient care options for symptomatic uterine fibroids.
The location sits on Commonwealth Drive, about a quarter of a mile from Patewood Drive and Roper Mountain Road Extension. Rocky Creek runs nearby, and the Roper at Pelham neighborhood is located about four-tenths of a mile away. The Greenville Health System Patewood Medical Campus is also situated roughly four-tenths of a mile from the hospital.
The hospital holds a rating of 3.70 based on 431 reviews, reflecting an established track record built on a large base of customer feedback. This volume of patient experience underscores its role as a major healthcare provider in the region.
Bon Secours St. Francis Eastside combines a broad spectrum of inpatient and outpatient services with specialized surgical and diagnostic capabilities, serving as a central hub for healthcare in Greenville.
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