Sandra Weiss, MD

Sandra Weiss, MD is a cardiologist in Wilmington, DE, specializing in interventional cardiology and serving patients across the region. She provides care for adolescents, adults, and older adults, with a focus on coronary and peripheral interventions, including the use of radial artery catheterization, a technique she helped implement to improve patient outcomes. Dr. Weiss is board certified in both general and interventional cardiology and serves as Medical Director of the Cardiac ICU at ChristianaCare. She is actively involved in research and has published multiple peer-reviewed articles. Her practice is based at ChristianaCare Cardiology at Avenue North, where she sees new patients and participates in multidisciplinary programs such as the Critical Limb Ischemia initiative.

Dr. Weiss brings extensive training and experience to her practice, having earned her undergraduate degree from Northwestern University in 2000 and her medical degree from the University of Chicago Pritzker School of Medicine in 2004. She completed her internal medicine residency at Brigham and Women’s Hospital in Boston and followed with fellowships in both general and interventional cardiology at the University of Chicago Medical Center. She has received notable honors, including the Internal Medicine Departmental Award and the American Medical Women’s Association Award, both from the University of Chicago in 2004. Her clinical work emphasizes patient-centered care, and she is a Fellow of the American College of Cardiology.

The practice is located on Silverside Road, just a short distance from the Wilmington Post Office, Talleyville Fire Company, and Concord Pike, with Springer Middle School and the Longwood neighborhood nearby. The office sits within a well-connected corridor of the city, accessible from major routes and surrounded by residential and civic infrastructure.

Dr. Weiss stands among the strongest in her category locally, recognized for her clinical expertise, leadership in cardiac care, and contributions to medical research. Her dedication to innovation and patient safety has helped shape modern interventional practices at ChristianaCare. She continues to be a key figure in advancing cardiovascular health in the Wilmington area.